Mani Sadredini

Vitenskapelige publikasjoner

Hansen Haugsten, Marie; Sadredini, Mani ; Hasic, Almira; Eriksen, Morten; Stokke, Mathis Korseberg (2023). Myocardial oxidative stress is increased in early reperfusion, but systemic antioxidative therapy does not prevent ischemia-reperfusion arrhythmias in pigs. Frontiers in Cardiovascular Medicine. Vol. 10.
https://doi.org/10.3389/fcvm.2023.1223496

Andreassen, Kristine; Rixon, Chloe Louise; Hansen Haugsten, Marie; Hauge-Iversen, Ida Marie; Zhang, Lili; Sadredini, Mani ; Murugan Erusappan, Pugazendhi; Sjaastad, Ivar; Christensen, Geir; Haugaa, Kristina Ingrid Helena Hermann; Edvardsen, Thor; Lunde, Ida Gjervold; Stokke, Mathis Korseberg (2023). Beneficial effects of exercise initiated before development of hypertrophic cardiomyopathy in genotype-positive mice. American Journal of Physiology. Heart and Circulatory Physiology. Vol. 324.
https://doi.org/10.1152/ajpheart.00701.2022

Hansen Haugsten, Marie; Sadredini, Mani ; Hasic, Almira; Anderson, Mark E.; Sjaastad, Ivar; Stokke, Mathis Korseberg (2022). CaMKII and reactive oxygen species contribute to early reperfusion arrhythmias, but oxidation of CaMKIIδ at methionines 281/282 is not a determining factor. 12 s. Journal of Molecular and Cellular Cardiology. Vol. 175.
https://doi.org/10.1016/j.yjmcc.2022.12.002

Danielsen, Tore Kristian; Sadredini, Mani ; Manotheepan, Ravinea; Aronsen, Jan Magnus; Frisk, Michael; Hansen Haugsten, Marie; Andressen, Kjetil Wessel; Hougen, Karina; Levy, Finn Olav; Louch, William Edward; Sejersted, Ole M; Sjaastad, Ivar; Stokke, Mathis Korseberg (2021). Exercise training stabilizes RyR2-dependent Ca2+ release in post-infarction heart failure. Frontiers in Cardiovascular Medicine. Vol. 7.
https://doi.org/10.3389/fcvm.2020.623922

Sadredini, Mani ; Manotheepan, Ravinea; Lehnart, Stephan E.; Anderson, Mark E.; Sjaastad, Ivar; Stokke, Mathis K. (2021). The oxidation-resistant CaMKII-MM281/282VV mutation does not prevent arrhythmias in CPVT1. Physiological Reports. Vol. 9.
https://doi.org/10.14814/phy2.15030

Sadredini, Mani ; Hansen Haugsten, Marie; Frisk, Michael; Louch, William E.; Lehnart, Stephan E.; Sjaastad, Ivar; Stokke, Mathis Korseberg (2021). CaMKII inhibition has dual effects on spontaneous Ca²⁺release and Ca²⁺ alternans in ventricular cardiomyocytes from mice with a gain-of-function RyR2 mutation. American Journal of Physiology. Heart and Circulatory Physiology. Vol. 321.
https://doi.org/10.1152/ajpheart.00011.2021

Ottesen, Anett Hellebø; Carlson, Cathrine Rein; Eken, Olav Søvik; Sadredini, Mani ; Myhre, Peder Langeland; Shen, Xin; Dalhus, Bjørn; Laver, Derek R.; Lunde, Per Kristian; Kurola, Jouni; Lunde, Marianne; Hoff, Jon Erik; Godang, Kristin; Sjaastad, Ivar; Pettilä, Ville; Stridsberg, Mats; Lehnart, Stephan E.; Edwards, Andrew; Lunde, Ida Gjervold; Omland, Torbjørn; Stokke, Mathis Korseberg; Christensen, Geir Arve; Røsjø, Helge; Louch, William Edward (2019). Secretoneurin Is an Endogenous Calcium/Calmodulin-Dependent Protein Kinase II Inhibitor That Attenuates Ca2+-Dependent Arrhythmia. Circulation: Arrhythmia and Electrophysiology. Vol. 12.
https://doi.org/10.1161/CIRCEP.118.007045

Danielsen, Tore Kristian; Manotheepan, Ravinea; Sadredini, Mani ; Leren, Ida Skrinde; Edwards, Andrew; Vincent, Kevin P.; Lehnart, Stephan .; Sejersted, Ole M; Sjaastad, Ivar; Haugaa, Kristina; Stokke, Mathis Korseberg (2018). Arrhythmia initiation in catecholaminergic polymorphic ventricular tachycardia type 1 depends on both heart rate and sympathetic stimulation. PLOS ONE. Vol. 13:e0207100.
https://doi.org/10.1371/journal.pone.0207100

Sadredini, Mani ; Danielsen, Tore Kristian; Aronsen, Jan Magnus; Manotheepan, Ravinea; Hougen, Karina; Sjaastad, Ivar; Stokke, Mathis Korseberg (2016). Beta-adrenoceptor stimulation reveals Ca2+ waves and sarcoplasmic reticulum Ca2+ depletion in left ventricular cardiomyocytes from post-infarction rats with and without heart failure. PLOS ONE. Vol. 11.
https://doi.org/10.1371/journal.pone.0153887

Manotheepan, Ravinea; Danielsen, Tore Kristian; Sadredini, Mani ; Anderson, Mark E.; Carlson, Cathrine Rein; Lehnart, Stefan; Sjaastad, Ivar; Stokke, Mathis Korseberg (2016). Exercise training prevents ventricular tachycardia in CPVT1 due to reduced CaMKII-dependent arrhythmogenic Ca2+ release. Cardiovascular Research (CVR). Vol. 111.
https://doi.org/10.1093/cvr/cvw095

Formidling

Efstathiou, Sofia; Sadredini, Mani ; Coutinho, Silvia Ribeiro (2022). MEAT meets! Mani Sadredini.
https://youtu.be/7uJfWY4UaI4

Danielsen, Tore Kristian; Manotheepan, Ravinea; Sadredini, Mani ; Leren, I.S.; Edwards, Andrew; Vincent, K.; Lehnart, Stefan; Sejersted, Ole M; Sjaastad, Ivar; Haugaa, Kristina; Stokke, Mathis Korseberg (2016). Mechanisms underlying the frequency-dependence of triggered arrhythmias in catecholaminergic polymorphic ventricular tachycardia type 1. 14th Annual CHFR Symposium on Heart Failure. Center for Heart Failure Research.

Manotheepan, Ravinea; Danielsen, Tore Kristian; Saberniak, Jorg; Sadredini, Mani ; Anderson, Mark e.; Carlson, Cathrine Rein; Edvardsen, Thor; Lehnart, Stefan; Sjaastad, Ivar; Haugaa, Kristina; Stokke, Mathis Korseberg (2016). Exercise training as anti-arrhythmic therapy in cathecholaminergic polymorphic ventricular tachycardia type 1. Norwegian Society of Cardiology, Autumn Meeting. Norwegian Society of Cardiology.

Sadredini, Mani ; Manotheepan, Ravinea; Danielsen, Tore Kristian; Lehnart, Stefan; Sjaastad, Ivar; Stokke, Mathis Korseberg (2016). Epac2 inhibition reduces arrhythmogenic Ca2+ wave frequently in cardiomyocytes from mice With catecholaminergic polymorphic ventricular tachcardia type 1. 14th Annual CHFR Symposium. Center for Heart Failure Research.

Sadredini, Mani Nikoo ; Danielsen, Tore Kristian; Aronsen, Jan Magnus; Manotheepan, Ravinea; Hougen, Karina; Sjaastad, Ivar; Stokke, Mathis Korseberg (2015). Beta-adrenoceptor stimulation reveals Ca2+ overload paradox in left ventricular cardiomyocytes from post-infarction rats with and without heart failure. 7th National PhD Conference in Medical Imaging. MedIM and Intervention Centre.

Danielsen, Tore Kristian; Manotheepan, Ravinea; Sadredini, Mani Nikoo ; Gaur, Namit; Leren, IS; Edwards, Andrew; Sejersted, Ole M; Lehnart, Stefan; Sjaastad, Ivar; Haugaa, Kristina; Stokke, Mathis Korseberg (2015). Mechanisms for the frequency-dependence of triggered activity in catecholaminergic polymorphic ventricular tachycardia type 1. 13th Annual CHFR Meeting. Center for Heart Failure Research.

Manotheepan, Ravinea; Danielsen, Tore Kristian; Sadredini, Mani Nikoo ; Anderson, Mark e.; Carlson, Cathrine Rein; Lehnart, Stefan; Sjaastad, Ivar; Stokke, Mathis Korseberg (2015). Exercise training reduced CaMKII-dependent arrhythmogenic Ca2+ release and prevents ventricular tachycardia in CPVT 1. 13th Annual CHFR Symposium on Heart Failure. Center for Heart Failure Research.

Sadredini, Mani Nikoo ; Danielsen, Tore Kristian; Aronsen, Jan Magnus; Manotheepan, Ravinea; Hougen, Karina; Sjaastad, Ivar; Stokke, Mathis Korseberg (2015). Beta-adrenoreceptor stimulation reveals Ca2+ overload paradox in left ventricular cardiomyocytes from post-infarction rats with and without heart failure. 13th Annual CHFR Symposium on Heart Failure. Center for Heart Failure Research.

Manotheepan, Ravinea; Danielsen, Tore Kristian; Sadredini, Mani Nikoo ; Lehnart, Stefan; Sjaastad, Ivar; Stokke, Mathis Korseberg (2014). Exercise training reduces CaMKII-dependent phosphorylation of the cardiac ryanodine receptor and arrhythmogenic SR Ca2+ leak in mice with mutant cardiac ryanodine receptor 2. National PhD Conference in Medical Imaging and MedViz Conference. MedViz.

Manotheepan, Ravinea; Danielsen, Tore Kristian; Sadredini, Mani Nikoo ; Anderson, Mark E.; Lehnart, Stephan; Sjaastad, Ivar; Stokke, Mathis Korseberg (2014). Exercise training reduces CaMKII-dependent phosphorylation of RyR2 and arrhythmogenic SR Ca2+ release in mince with CPVT. 12th Annual Center for Heart Failure Symposium. Center for Heart Failure.