Forskningsgrupper
Forskningsprosjekter
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Persontilpassa legemiddelbehandling – legemiddelanalysar og farmakogenetikk
Dette prosjektet er ei kartlegging av variasjon i eksponering og respons av psykofarmakum.
Publikasjoner og forskningsresultater
Vitenskapelige publikasjoner
Faraj, Pari;
Haslemo, Tore
; Tran, Jenny Phung; Stingl, Julia; Molden, Espen;
Hole, Kristine
(2024).
Combined effect of CYP2C19 and CYP2D6 genotypes on escitalopram serum concentration and its metabolic ratio in a European patient population.
British Journal of Clinical Pharmacology.
https://doi.org/10.1111/bcp.16156
Hole, Kristine
; Lorentsen, Silje K; Nordby, Karoline L; Sørum, Ida TG; Molden, Espen;
Haslemo, Tore
(2024).
Dose-dependent effect of lamotrigine on quetiapine serum concentration in patients using instant release tablets.
European Journal of Clinical Pharmacology.
https://doi.org/10.1007/s00228-024-03655-z
Hole, Kristine
; Gangsø, Sofie; Jensstuen, Åse Tonette; Ormøy, Hanne Holte; Paulsen, Maren; Molden, Espen;
Haslemo, Tore
(2023).
Effect of CYP2D6 genotype on duloxetine serum concentration.
Basic & Clinical Pharmacology & Toxicology.
Vol. 134.
https://doi.org/10.1111/bcpt.13954
Hole, Kristine
;
Haslemo, Tore
; Molden, Espen
(2023).
Impact of CYP2D6 Genotype on Paroxetine Serum Concentration.
5 s.
Therapeutic Drug Monitoring.
Vol. 45.
https://doi.org/10.1097/FTD.0000000000001096
Solhaug, Vigdis;
Haslemo, Tore
;
Kringen, Marianne Kristiansen
; Molden, Espen; Dietrichs, Erik Sveberg
(2022).
Genotyping av pasienter behandlet med selektive serotoninreopptakshemmere.
9 s.
Tidsskrift for Den norske legeforening.
Vol. 142.
https://doi.org/10.4045/tidsskr.22.0017
Hole, Kristine
; Arnestad, Marianne; Molden, Espen;
Haslemo, Tore
(2021).
Dose-Dependent Inhibition of CYP2D6 by Bupropion in Patients with Depression.
4 s.
Journal of Clinical Psychopharmacology.
Vol. 41.
https://doi.org/10.1097/JCP.0000000000001387
Tveito, Marit; Høiseth, Gudrun;
Haslemo, Tore
; Molden, Espen; Smith, Robert Løvsletten
(2021).
Impact of age and gender on paliperidone exposure in patients after administration of long-acting injectable formulations—an observational study using blood samples from 1223 patients.
European Journal of Clinical Pharmacology.
Vol. 77.
https://doi.org/10.1007/s00228-021-03114-z
Bråten, Line Skute;
Haslemo, Tore
; Jukić, Marin M.; Ivanov, Maxim; Ingelman-Sundberg, Magnus; Molden, Espen;
Kringen, Marianne K.
(2021).
A Novel CYP2C-Haplotype Associated With Ultrarapid Metabolism of Escitalopram.
Clinical Pharmacology and Therapeutics.
Vol. 110.
https://doi.org/10.1002/cpt.2233
Kringen, Marianne K.
; Bråten, Line Skute;
Haslemo, Tore
; Molden, Espen
(2020).
The Influence of Combined CYP2D6 and CYP2C19 Genotypes on Venlafaxine and O -Desmethylvenlafaxine Concentrations in a Large Patient Cohort.
7 s.
Journal of Clinical Psychopharmacology.
Vol. 40.
https://doi.org/10.1097/JCP.0000000000001174
Gjestad, Caroline;
Hole, Kristine
;
Haslemo, Tore
; Diczfalusy, Ulf; Molden, Espen
(2019).
Effect of Grapefruit Juice Intake on Serum Level of the Endogenous CYP3A4 Metabolite 4β-Hydroxycholesterol—an Interaction Study in Healthy Volunteers.
7 s.
AAPS Journal.
Vol. 21.
https://doi.org/10.1208/s12248-019-0330-1